Cytisine for smoking cessation
Cytisine for smoking cessation Abstract Cigarette smoking is the one of the major risk factor for human health. The treatment of smoking addiction is changing rapidly through different natural and artificial substances. Among them Cytisine is playing one of the major role. Cytisine, also known as baptitoxine and sophorine , is an alkaloid that occurs naturally in several plant genera , such as Laburnum and Cytisus of family Fabaceae and usually extracted from the seeds of those plants. Cytisine is an acetylcholine agonist , and has strong binding affinity for the nicotinic acetylcholine receptor. Cytisine plays the part of a nicotine- substitute substance which decreases the period of interaction between nicotine and the corresponding receptors. This in turn leads to a gradual decrease and interruption of the smoker’s psychic and physical nicotine dependence. The use of cytisine for smoking cessation remains relatively unknown outside Eastern Europe. This review is about th...