MCQ BIOLOGY BIOMOLECULES 12.07.2021

 

1.The mature erythrocyte contains

a) Cytochromes                        

b) TCA – enzymes

c) Pyruvic kinase                      

d) ATP – ase

2. Hemoglobin is responsible for what percentage of carbondioxide transport by the blood ?

a) 90                  

b) 50                  

c) 10                  

d) 5

3. Christmas factor is synonymous with

a) Proconvertin                         

b) Antihemophilic factor – B

c) Platelet accelerator                    

d) Factor XI

4. Blood plasma differs from blood serum in content of

a) Lipid                                

b) Erythrocytes

c) Protein                                     

d) Carbohydrate

5. The naturally occurring porphyrins are

a) Usually associated with a metal

b) Usually associated with an unchanged metaltion

c) Only found in animals       

d) Usually chains of pyrrole rings

6. Among the anticoagulants normally present in an animal is

a) Dicumarol                              

b) Heparin      

c) Vitamin – K                   

d) Lipoprotion lipase

7. Which is not a part of the hemoglobin molecule ?

a) Histidine     

b) Protein        

c) Ferricion    

d) Vinyl groups

8. The normal P^H of blood is

a) 7.4                

b) 6.8                

c) 7.7                

d) 7.1

9. Oxidation of which substance yields the most calories per gram ?

a) glucose      

b) Lipid   

c) Animal protein  

d) Glycogen

10. A negative nitrogen balance is observed

a) During normal pregnancy                  

b) During normal child growth

c) During convalescence               

d) In malnutrition

11. The major pathway for calcium excretion under normal condition is

a) Feces 

b) Sweat

c) Urine  

d) Milk

12. The biological value of protein depends upon

a) The digestibility alone

b) Digestibility and amino acid composition

c) Amino acid composition alone         

d) Digestibility and leucine

13. Tetany due to hypocalcemia results from remove of the

a) Parathyroids      

b) Thyroids     

c) Pituitary      

d) Adrenals

14. The ingestion of which food-stuff results in the gretest specific dynamic action ?

a) Fat                

b) Carbohydrate    

c) Protein        

d) Vitamins

15. Ferritin is found in

a) Liver   

b) Kidney        

c) Pancreas   

d) Bone

16. A hyperglycemic factor produced by the pancreas is

a) Insulin

b) Glucagon   

c) FSII               

d) ACTH

17. The prostaglandins

a) Cause hypertension                              

b) Occur only in prostatic tissue

c) Are alicyclic fatty acid derivatives           

d) Are synthesized from olec acids

18. How many different codons are capable of terminating polypeptide chain elongation in protein synthesis ?

a) One              

b) Two              

c) Three 

d) Four

19. Transsiation results in a product known as

a) Protein        

b) t-RNA 

b) m-RNA        

d) DNA

20. A potent inhibitor of protein synthesis that acts as on analogue of amino acyl t-RNa is

a) Mitomycin – C    

b) Streptomycin     

c) Rifampicin          

d) Puromycin

21. Nucleotides are linked to one another in RNA by one of the following ?

a) Phosphate ester bond                

b) Phosphodiester bond

c) Glycosidic bond                            

d) Hydrophobic bond

22. One of the following is a stable isotope

a) ¹⁵H                

b) ¹⁴C                

c) ³²P                 

d) ¹³¹I

23. One of the following is a radioactive isotope

a) ²H                  

b) ¹⁵C                

c) ¹³P                 

d) ³I

24. In ELISA  the enzyme label for the antibody may be

a) Glucose oxidase                                     

b) Amylase

c) Lipase                                      

d) Succinic dehydrogenase

25. The half-life of ¹⁴C isptope is

a) 51 years     

b) 5100 years          

c) 510 years   

d) 5 years

26. GM-counter is used to measure

a) Gamma – radiation                                

b) Protons       

c) Beta – radiation                             

d) Alpha – radiation

27. Kwashiorker results from

a) Vitamin A deficiency                   

b) Vitamin D deficiency

c) Mineral deficiency in diet                   

d) Protein and calorie deficiency in diet

28.Soya-bean proteins are rich in

a) Lysine

b) Alanine       

c) Glycine       

d) Proline

29. Inactive plasminogen is activated by

a) Fibrinogen          

b) Fibrin 

c) Thrombin   

d) Calcium ions

30. The following enzyme is found to the cell membrane

a) Sodium – Potassium ATP ase  

b) Lipase

c) Pepsin         

d) Hexokinase

31.One of the following is not estimated by RIA

a) T₃         

b) T₄

c) Insulin

d) ²H – testosterone

32. The micro organism that can cause jaundice is

a) Steptococus faecalis                           

b) Escherechia coli

c) Plasmodium sp.                             

d) Salmonella typhimurium

33. Zine is a constituent of the enzyme

a) Lactate dehydrogenase                      

b) Glutamate dehydrogenase

c) Carbonic anhydrase                             

d) Transketolase

34. Immine lymphocytes

a) Produce only m - chains

b) Are progenitors of T as well as B lymphocytes

c) Express IgM on their cell surface

d) Must go through the thymus to mature

 

35. Antigen is initially presented to T-lymphocytes by

a) Macrophages    

b) Neutrophils                  

c) Plasma cells                

d) Platelets

36. The codon for phenylalanine is

a) AAA    

b) CCC    

c) GGG   

d) UUU

37. Retriction enzymes have been found in

a) Humans      

b) Birds  

c) Bacteria     

d) Bacterio phages

38. Sigma and Rhofactors arre required for

a) Replication                  

b) Transcription     

c) Translation         

d) Polymerization

39. Okasaki fragments are small bits of

a) RNA    

b) DNA    

c) DNA with RNA heads         

d) RNA with DNA heads

40. DNA directed RNA polymerase is

a) Replicase                                         

b) Transcriptase

c) Reverse transcriptase                         

d) Polymerase III

41. In competitive inhibition

a) The K_m is unchanged        

b) The K_m        

c) V_max is decreased      

d) V_max is unchanged

 

42. K_m is

a) The substrate concentration that gives half-maximal velocity.   

b) The dissociation constant for the ES-complex       

c) Equal to half the substrate concentration required to achieve maximal velocity  

d) Identical for all isozymes of an enzyme.

 

43. An enzyme of saliva that hydrolyses starch is

a) Pepsin         

b) b-amylase  

c) a-amylase  

d) Maltase

44. Which one of the following is an essential cofactor in carboxylation reactions?

a) Coenzyme A       

b) CTP              

c) Lipoic acid          

d) Biotin

45. A specific poison for succinic dehydrogenase is

a) Malonate    

b) Arsenite     

c) Cyanide      

d) Malate

46. The coenzyme for tranketolase is

a) Coenzyme A       

b) NAD⁺  

c) FMN    

d) TPP

47. Which one of the following is not a component of coenzyme A?

a) Adenylic acid    

b) Acetic acid          

c) Pantothenic acid       

d) Cysteamine

48. Dehydrogenases wue as coenzymes all of the following, except

a) NAD⁺  

b) FAD    

c) FMN    

d) Ferriprotoporphyrin

49. Urea is produced by the enzyme

a) Urease        

b) Glutaminase      

c) Arginase    

d) Uricase

50. The specific substrate for oxidative phosphorylation is

a) AMP    

b) ADP    

c) ATP              

d) NADP⁺

51. An enzyme not involved in glycolysis is

a) Aldolase                                  

b) a- glycerophosphate dehydrogenase

c) Enolase                                   

d) Pyruvate kinase

52. Dehydrogenases of the hexose monophosphate shute are specific for

a) NAD⁺  

b) FAD    

c) NADP⁺

d) FMN

53. When one molecule of glucose is completely oxidized in vivo, how many ATP molecules are formed ?

a) 2           

b) 12                  

c) 24                  

d) 36

54. Which amino acid undergoes transamination to form a - ketoisocaproic acid ?

a) Leucine      

b) Isoleucine           

c) Valine

d) Lysine

55. For the conversion of dUMP to TMP, which one of the following is required ?

a) Tetrahydrofolic acid

b) ATP              

c) FMN    

d) Pyridophate

56. Kinases require

a) Mg⁺⁺    

b) Mn⁺⁺    

c) Inorganic phosphate         

d) EDTA

57. A fatty acid not synthesized in man is

a) Oleic acid           

b) Linoleic      

c) Stearic acid                 

d) Palmitic acid

58. The major site of aceto acetate formation from fatty acids is the

a) liver              

b) kidney

c) Lungs 

d) Muscle

59. An amino acid not involved in urea synthesis is

a) Arginine     

b) Histidine     

c) Citrulline    

d) Omithine

60. An essential amino acid in man is

a) Proline        

b) Serine

c) Methionine         

d) Tyrosine

61. Which amino acid possesses two as symmetric carbon atoms

a) Valine

b) Leucine      

c) Histidine     

d) Isoleucine

62. An animal is in positive nitrogen balance when

a) Nitrogen intake exceeds output                

b) Nitrogen output exceeds intake

c) Urine is nitrogen free                           

d) Urine contains nitrogen

63. The biological activity of the tocopherols has been attributed to their action as

a) Antioxidants                                    

b) Carriers in the electron transport chain

c) Anticogulants                                 

d) Precursors of vitamin A

64. Vitamin K plays an essential role in

a) Preventing thrombasis

b) The biosynthesis of prothrombin and proconvertin

c) maintaining retinal integrity    

d) Preventing bile stasis

65. A vitamin that acts as a reducing agent is

a) Nicotinamide     

b) Riboflavin  

c) Ascorbic acid    

d) Folic acid

66. Vitamin B₁₂ is a

a) Porphyrin like compound                             

b) Fat-solube vitamin

c) Vitamin synthesized by all animals except man     

d) Copper-containing B-vitamin

67. The growth of bacteria requiring p-aminobenzoic acid is inhibited by

a) Folic acid                               

b) Tetrahydrofoli acid   

c) Citrovorum factor                         

d) Sulfonamides

68. Whole wheat is an excellent source of

a) Thiamine    

b) Vitamin-A            

c) Ascorbic acid    

d) Vitamin-D

69. In man, the principal catabolic product of purines is

a) Allantoin    

b) Urea   

c) Uric acid    

d) Ammonia

70. A key substance in pyrumidine biosynthesis is

a) ATP              

b) Carbamoyl phosphate      

c) THiourea    

d) NADP⁺

71. Inulin is a

a) Fructosan  

b) Glucosan   

c) Xylan  

d) Hormone

72. Choline is

a) Amino acid

b) Fatty acid   

c) Quaternary base       

d) Sugar

73. Collagen is very rich in

a) Glycine       

b) Serine

c) Aspartic acid     

d) Glutamic acid

74. The following is not used in gel electrophoresis

a) Agar   

b) Starch

c) Polyacry lamide

d) Alumina

75. The common stain for proteins in electrophoresis is

a) Bromophenol blue              

b) Oil red O     

c) Congo red 

d) Ninhydrin

76. T L C  is very useful to determine

a) Iodine number                      

b) Acetyl number

c) Saponification value         

d) Fatty acid composition

77. In molecular exclusion chromatography the following one will come as a first fraction

a) Protein        

b) Amino acids       

c) sodium chloride         

d) Sugars

78. The high acidity of cation exchange is due to

a) –COOH       

b) –SO₃H

c) Phenolic group 

d) Enolic group

79. For separation of proteins and nucleic acids the following ion-exchange resin is preferred

a) Alumina      

b) Dowex         

c) DEAE cellulose 

d) Amberlite

80. The instrument commonly used to estimate electrolytes is

a) Spectro photometer                    

b) Colori meter

c) Polari meter                                    

d) Flame photo meter

81. Keratin is a

a) Fibrous protein 

b) Glubulin     

c) Histone       

d) Conjugated protein

82. Histones

a) Are proteins rich in lysine and arginine

b) Are bound convalently to DNA

c) Are indentical to protamines

d) Have relatively very high molecular weights

83. Which one of the following polysaccharides is not a polymer of glucose ?

a) Amylose     

b) Amylopectin       

c) Glycogen             

d) Inulin

84. Reduction of glucose with calcium in water produces

a) Sorbitol       

b) Dulcitol       

c) Mannitol     

d) Sorbose

85. Cytochromes are

a) Riboflavin containing nucleotides            

b) Pyridine nucleotides

c) Iron – Porphyrin proteins                    

d) Metal containing flavoproteins

86. Chemically heparin ia a

a) Purine

b) Protein        

c) Lipid   

d) Carbohydrate

87. The Beer – Lambert law relates absorbance with

a) Concentration of solute and pathength of the solution cell

b) Concentration of solute and height of the solution cell

c) Length and heights of solution column

d) Intensities of incident and transmitted lights

88. Sphingosine is

a) Unsaturated fatty acid                

b) Saturated  fatty acid

c) Sterol                              

d) Complex amino alcohol

89. Liebermann – Buchard reaction is to detect

a) Glycerol     

b) Oleic acid  

c) Cholesterol                  

d) Cerebroside

90. Iodine value of an oil shows the extent of

a) Poymerization   

b) Unsaturation      

c) Molecular size  

d) Esterification